Acute Lung Disease

We study the mechanisms and patterns of acute lung disease in sickle cell mice to develop new treatments for acute chest syndrome.


We are testing new ways to measure and treat pain in patients with sickle cell disease.

Pulmonary Hypertension

We study how sickle cell disease promotes pulmonary hypertension in mice and in patients, and we are testing new medications.


We are developing new apps and methods to study and treat complications of sickle cell disease.

Patient Care

UPMC has sickle cell patient care programs for children and adults with sickle cell disease and other related blood diseases.


We study high resolution MRI brain imaging, neurocognition, and thrombospondin-1 in adults with SCD.