At the University of Pittsburgh, we’re dedicated to developing new and effective therapies for sickle cell disease with the ultimate goal of finding a cure accessible to all.
Since the scientific community now has a greater understanding of the basic molecular processes and issues associated with sickle cell disease, we can devote many of our research efforts to clinical issues, such as specific treatment therapies, and developing gene-based therapeutics that will lead to a cure.
Why Are Clinical Trials Important?
Clinical research trials, typically just referred to as clinical trials, play a critical role in the advancement of medical knowledge.
By conducting clinical trials, we can:
- Learn how a new therapeutic medicine or treatment works in humans
- Learn which treatment strategies work well and which do not
- Discover new and better ways to prevent, diagnose, and treat complications of sickle cell disease
- Get closer to discovering a cure for sickle cell disease and related hemoglobinopathies that will work for a majority of patients
|iCanCope With Sickle Cell Disease: a Computerized Cognitive Behavioral Therapy Program for Pain Management (iCanCopeSCD)||NCT03029468||Charles Jonassaint, PhD|
|A Multi-Center Study of Riociguat in Patients With Sickle Cell Diseases||NCT02633397||Greg Kato, MD|
|Feasibility Study of Unfractionated Heparin in Acute Chest Syndrome||NCT02098993||Craig Seaman, MD
Margaret Ragni, MD, MPH
|Neurovascular Determinants of Cognitive Function in Adults With Sickle Cell Disease||NCT02946905||Enrico Novelli, MD, MS|
|A Phase Ib Study of NVX-508 in Sickle Cell Disease||NCT03013426||Amma Owusu-Ansah, MD|
|Study to Evaluate the Effect of GBT440 Administered Orally to Patients With Sickle Cell Disease (GBT_HOPE)||NCT03036813||Jude Jonassaint|
|Efficacy and Safety of Rivipansel (GMI-1070) in the Treatment of Vaso-Occlusive Crisis in Hospitalized Subjects With Sickle Cell Disease||NCT02187003||ClinicalTrials.gov_Inquiries@pfizer.com|