Publications

  • Intravascular hemolysis and the pathophysiology of sickle cell disease.

    Related ArticlesIntravascular hemolysis and the pathophysiology of sickle cell disease. J Clin Invest. 2017 Mar 01;127(3):750-760 Authors: Kato GJ, Steinberg MH, Gladwin MT Abstract Hemolysis is a fundamental feature of sickle cell anemia that contributes to its pathophysiology and phenotypic variability. Decompartmentalized hemoglobin, arginase 1, asymmetric dimethylarginine, and adenine nucleotides are all products of hemolysis that promote vasomotor […]